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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Eur J Cancer. 2020 Jan 8;126:78–90. doi: 10.1016/j.ejca.2019.12.006

Figure 3. Landmark analysis of PFS24 based on radiographic imaging at time of treatment in patients treated with R-CHOP.

Figure 3.

Kaplan-Meier plots of overall survival (OS) since 2 years landmark stratified by PFS24 status in patients with stage II-IV disease treated with R-CHOP. (A) MSKCC cohort. (B) Validation FOLL05 cohort. When comparing OS by PFS24 status, PFS24 failures staged by CT had a worse outcome than those who were staged with PET. For CT-staged patients who failed PFS24, the estimated 10-year OS rate was 47% versus PET-staged that was 76%. The results were reproduced in the validation cohort where CT-imaged PFS24 failures had an estimated 5-year OS rate of 56% versus PET-imaged PFS24 failures had an estimated 5-year OS rate of 100%.