Table 2.

Rate of histological transformation and risk of death based on PFS24 status. Risk of transformed FL denotes the culminative risk of biopsy-proven transformation at the time of the relapse. The culminative risk of death without transformation is provided using a competing risk analysis. The risk of death due to transformation is calculated by the total risk of death minus the risk of death without transformation.

	Years after risk-defining event	Progression within 1 year (n=44); cumulative risk (cumulative cases)	Progression between 1–2 year (n=54); cumulative risk (cumulative cases)	PFS24 achievers (n=248); cumulative risk (cumulative cases)
Risk of tFL,%	0·02 (1 week)	9·1 (4)	5·6 (3)	0·0 (0)
	1	31·9 (14)	18·6 (10)	0·0 (0)
	2	34·5 (15)	18·6 (10)	2·1 (5)
	3	42·4 (18)	22·7 (12)	3·4 (8)
Risk of death due to tFL,%	0·02 (1 week)	0·0 (0)	0·0 (0)	0·0 (0)
	1	11·4 (5)	5·7 (3)	0·0 (0)
	2	16·2 (7)	7·7 (4)	0·0 (0)
	3	18·6 (8)	9·8 (5)	0·9 (2)
Risk of death without tFL,%	0·02 (1 week)	0·0 (0)	0·0 (0)	0·0 (0)
	1	9·1 (4)	3·8 (2)	1·2 (3)
	2	11·7 (5)	5·8 (3)	1·6 (4)
	3	14·4 (6)	12·0 (6)	2·5 (6)
Total risk of death (sum of risk of death from tFL and without tFL),%	0·02 (1 week)	0·0 (0)	0·0 (0)	0·0 (0)
	1	20·5 (9)	9·4 (5)	1·2 (3)
	2	27·8 (12)	13·6 (7)	1·6 (4)
	3	33·0 (14)	21·8 (11)	3·4 (8)