Table 4.
AUC (95% CI) | p valuea | Sensitivity (%) (95% CI) |
Specificity (%) (95% CI) |
Youden index | Cut-off value | p valueb | NRI | |
---|---|---|---|---|---|---|---|---|
Prediction for total prognoses | ||||||||
NLR | 0.69 (0.637–0.734) | <0.001 | 64.54 (0.583–0.706) | 67.49 (0.606–0.739) | 0.32 | 2.59 | 0.035 | — |
CRP | 0.74 (0.695–0.786) | <0.001 | 61.48 (0.552–0.674) | 78.17 (0.719–0.834) | 0.39 | 10.85 mg/L | 0.009 | — |
Prediction for severe progression | ||||||||
NLR | 0.62 (0.565–0.681) | <0.001 | 54.19 (0.463–0.618) | 67.49 (0.608–0.736) | 0.22 | 2.60 | 0.343 | — |
CRP | 0.67 (0.609–0.725) | <0.001 | 45.39 (0.377–0.533) | 81.73 (0.757–0.865) | 0.28 | 14.15 mg/L | 0.646 | — |
Prediction for critical progression | ||||||||
NLR | 0.77 (0.694–0.846) | <0.001 | 76.00 (0.618–0.869) | 68.97 (0.621–0.753) | 0.45 | 2.79 | 0.635 | ref |
CRP | 0.84 (0.780–0.905) | <0.001 | 78.00 (0.645–0.872) | 67.49 (0.608–0.735) | 0.45 | 25.95 mg/L | 0.134 | 15.52 |
Prediction for in-hospital death | ||||||||
NLR | 0.81 (0.732–0.878) | <0.001 | 78.26 (0.637–0.891) | 73.89 (0.673–0.798) | 0.52 | 3.16 | 0.059 | ref |
CRP | 0.89 (0.825–0.946) | <0.001 | 67.44 (0.525–0.7951) | 0.929 (0.884–0.957) | 0.60 | 33.40 mg/L | 0.121 | 31.75 |
PCT | 0.89 (0.835–0.962) | <0.001 | 73.81 (0.589–0.847) | 93.62 (0.892–0.963) | 0.67 | 0.85 ng/mL | <0.001 | — |
Abbreviations: AUC, area under the curve; CRP, C-reactive protein; NLR, neutrophil count/lymphocyte count ratio; NRI, net reclassification index.
p value for ROC curve.
p value for Hosmer–Lemeshow test.