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Polyprotein cleavage sites recognised by Mpro of SARS-CoV-2, SARS-CoV and MERS-CoV. Peptide sequences cover residues P5 to P5′ according to the nomenclature of Schechter and Berger.81 Data were generated from pp1ab polyprotein sequences reported in the UniProt database with the accession codes P0DTD1 (SARS-CoV-2), P0C6X7 (SARS-CoV) and K9N7C7 (MERS-CoV). The consensus sequence over all cleavage sites was plotted using WebLogo.86.
