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. 2020 Jun 25;13:85. doi: 10.3389/fnmol.2020.00085

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Copyright © 2020 O’Hare Doig, Santhakumar, Fehily, Raja, Solomon, Bartlett, Fitzgerald and Hodgetts.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of Lom, oxATP, and YM872 on lipid peroxidation by-products, 4-hydroxynonenal (HNE), and acrolein, at 2W and 10W post-SCI. (A–D) Mean ± SEM intensity above the threshold of lipid peroxidation by-products 4-hydroxynonenal (HNE) (A) and acrolein (C; n = 6–7; *p ≤ 0.05). Representative images show areas of HNE^+ve (blue; B) and acrolein^+ve (cyan; D) immunoreactivity surrounding the injury site (scale bars = 500 μm; n = animal numbers).