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. 2020 Jul 2;10:10923. doi: 10.1038/s41598-020-67934-2

Figure 1.

Figure 1

(A) S-GFAP and s-NfL levels are correlated in MS patients (r = 0.66, p = 1e−06). Serum and CSF GFAP (B) and NfL (C) were correlated (r = 0.58, p = 1e−04 and r = 0.48, p = 0.0012). s-GFAP (D) and s-NfL (E) levels are higher in PPMS than in RRMS (respectively 130.3 ± 72.8 vs 83.4 ± 41.1 pg/ml and 13.63 pg/ml 6.60 vs. 9.33 pg/ml 4.52 pg/ml). S-GFAP is correlated with white matter lesions volume (F, r = 0.39, p = 0.0093) and is negatively correlated with white matter (G, r = − 0.4, p = 0.063), grey matter (H, r =  − 0.38, p = 0.0093) and cortical grey matter (I, r = − 0.37, p = 0.0115) volumes.