Table 1.
Demographic and clinical characteristics of study population.
| Phenotype | Lean |
Overweight |
Obese |
Lean versus overweight |
Lean versus obese |
|---|---|---|---|---|---|
| (n = 10) (Mean ± SD) | (n = 20) (Mean ± SD) | (n = 29) (Mean ± SD) | (p value) | (p value) | |
| Age (years) | 42.7 ± 8.17 | 43.05 ± 11.19 | 45.41 ± 13.15 | 0.931 | 0.546 |
| Weight (kg) | 62.93 ± 11.90 | 79.49 ± 9.66 | 93.84 ± 13.77 | <0.0001 | <0.0001 |
| Height (cm) | 1.66 ± 0.12 | 1.67 ± 0.11 | 1.64 ± 0.10 | 0.701 | 0.659 |
| BMI (kg/m2) | 22.82 ± 2.35 | 28.30 ± 1.17 | 34.87 ± 3.30 | <0.0001 | <0.0001 |
| Waist (cm) | 81.33 ± 12.44 | 95.19 ± 8.81 | 106.74 ± 12.86 | 0.003 | <0.0001 |
| Body fat (%) | 28.37 ± 6.27 | 32.52 ± 4.87 | 39.56 ± 4.25 | 0.073 | <0.0001 |
| TGL (mmol/l) | 0.63 ± 0.24 | 1.21 ± 0.62 | 1.35 ± 0.86 | 0.001 | <0.0001 |
| FBG (mmol/l) | 4.97 ± 0.64 | 5.24 ± 0.67 | 5.37 ± 0.77 | 0.292 | 0.151 |
| HbA1c (%) | 5.66 ± 0.46 | 5.51 ± 0.44 | 5.69 ± 0.65 | 0.388 | 0.884 |
| Chol (mmol/l) | 5.3 ± 1.11 | 4.97 ± 0.71 | 5.03 ± 1.14 | 0.323 | 0.521 |
| HDL (mmol/l) | 1.69 ± 0.51 | 1.26 ± 0.29 | 1.16 ± 0.27 | 0.006 | 0.009 |
| LDL (mmol/l) | 3.31 ± 0.93 | 3.18 ± 0.65 | 3.28 ± 1.01 | 0.659 | 0.933 |
| WBC | 5.57 ± 1.60 | 6.25 ± 1.52 | 6.58 ± 1.93 | 0.283 | 0.161 |
BMI, body mass index, Chol, cholesterol; FBG, fasting blood glucose; LDL, low-density lipoprotein; HbA1c, glycated hemoglobin; HDL, high-density lipoprotein; SD, standard deviation; TGL, plasma triglycerides.