Figure 1.
Recovery of sensory function following unilateral dorsal column lesion. (a) Experimental setup of the dorsal column lesion paradigm and behavioral testing. (b) Schematic drawing of the “placing test” and quantitative analysis of the scores obtained using the placing test at baseline and different time points following dorsal column lesion. (c) Schematic drawing of the “baton” test used to evaluate touch/proprioception in mice. Quantitative analysis of the scores obtained using the baton test at baseline and different time points following dorsal column lesion. Datasets were tested first for normality (non-normal distribution) and then analyzed using repeated unparametric ANOVA (Friedmann test) followed by post-hoc multiple comparison Dunn’s tests. “n” equals 12–13 per group. *** p < 0.001: 2 dpi injured vs baseline injured. ** p < 0.01: 2 dpi injured vs baseline injured. ## p < 0.01 84 dpi injured vs 2dpi injured. # p < 0.05: 14, 21, 42, 84 dpi injured vs 2 dpi injured.