Table 3. Comparison of Framingham Risk Score and Its Component Variables Between HIV-Positive and HIV-Negative Pre-Menopausal Women.
| Variables | HIV-positive pre-menopausal women (N = 25) | HIV-negative pre-menopausal women (N = 9,610) | P value |
|---|---|---|---|
| Age in years, mean (SD) | 39.44 (7.46) | 33.90 (8.94) | 0.147 |
| Systolic BP, mm Hg, mean (SD) | 113.4 (23.1) | 109.3 (18.6) | 0.215 |
| Diastolic BP*, mm Hg, mean (SD) | 67.23 (17.3) | 66.0 (13.8) | 0.136 |
| On medicines for BP, n (%) | 5 (20.0) | 930 (9.7) | 0.082 |
| Current smokers, n (%) | 0 (0.0) | 858 (8.9) | 0.242 |
| Hemoglobin A1c, mean (SD) | 5.27 (0.42) | 5.33 (0.79) | 0.531 |
| HDL cholesterol, mg/dL, mean (SD) | 45.4 (9.8) | 57.4 (16.2) | 0.050 |
| Total cholesterol, mg/dL, mean (SD) | 187.0 (42.5) | 192.5 (41.4) | 0.523 |
| C-reactive protein*, mg/dL, mean (SD) | 0.36 (0.31) | 0.51 (0.82) | 0.113 |
| Framingham 10-year risk score | 2.12 (2.73) | 0.95 (1.93) | 0.010 |
*Diastolic blood pressure and C-reactive protein are not part of the Framingham risk score. SD: standard deviation; BP: blood pressure; HDL: high-density lipoprotein; HIV: human immunodeficiency virus.