Table 1.
Comparison of Baseline Demographic and Characteristic Data Among PBC Waitlist Registrants by Ethnicity/Race,OPTN/UNOS 2000–2014
| All patients n = 5472 |
White n = 4179 |
Hispanic n = 793 |
African-American n = 299 |
Other n = 201 |
P value |
|
|---|---|---|---|---|---|---|
| Age (mean, SD) | 55.6 (9.1) | 56.2 (9.2) | 53.4 (9.5) | 52.59 (9.6) | 54.62 (9.2) | <.001 |
| Gender, n (%) | <.001 | |||||
| Female | 4714 (86.2) | 3559 (85.2) | 724 (91.3) | 262 (87.6) | 169 (84.1) | |
| Male | 758 (13.8) | 620 (14.8) | 69 (8.7) | 37 (12.4) | 32 (15.9) | |
| BMI (mean, SD) | 26.7 (5.4) | 26.8 (5.4) | 26.1 (5.0) | 27.8 (5.8) | 24.0 (4.7) | .126 |
| Albumin (mean, SD) | 3.00 (0.6) | 3.00 (0.6) | 2.9 (0.6) | 2.77 (0.7) | 2.92 (0.6) | <.001 |
| Total bilirubin (mean, SD) | 6.5 (5.6) | 5.88 (7.0) | 7.2 (8.7) | 10.12 (9.6) | 8.94 (10.0) | <.001 |
| Creatinine (mean, SD) | 1.1 (0.8) | 1.06 (0.7) | 1.0 (0.8) | 1.32 (1.3) | 1.06 (0.8) | <.001 |
| INR (mean, SD) | 1.40 (0.5) | 1.35 (0.4) | 1.40 (0.5) | 1.58 (0.8) | 1.41 (0.5) | <.001 |
| Diabetes, n (%) | 748 (13.7) | 520 (12.4) | 126 (15.9) | 66 (22.1) | 36 (17.9) | <.001 |
| HCC, n (%) | 71 (1.3) | 53 (1.2) | 12(1.5) | 3(1.0) | 3(1.5) | .902 |
| Laboratory MELD score at listing (mean, SD) | 16.4 (8.6) | 15.9 (8.8) | 16.8 (7.1) | 20.2 (8.0) | 16.1 (8.2) | <.001 |
| Portal hypertension complications, n (%) | ||||||
| Ascites | 3014 (55.1) | 2251 (53.9) | 465 (58.6) | 185 (61.9) | 113 (56.2) | .007 |
| SBP | 200 (3.6) | 140 (3.4) | 49 (6.2) | 5(1.7) | 6 | .002 |
| HE | 4227 (77.2) | 1164 (27.9) | 233 (29.4) | 107 (35.8) | 57 (28.4) | .030 |
| Living donor transplant, n (%) | 270 (9.9) | 233 (11.0) | 30 (8.3) | 7 (3.7) | 0 | <.001 |
| Liver transplant, n (%) | 2726 (49.8) | 2093 (50.1) | 353 (44.5) | 186 (62.2) | 94 (46.8) | <.001 |
| MELD score at transplant (mean, SD)a | 22.3 (9.3) | 21.3 (9.1) | 25.8 (10.3) | 24.9 (9.1) | 25.4 (10.4) | <.001 |
| Waitlist time (d) to transplant (median, SD) | 176 (554) | 179 (586) | 180 (472) | 98 (456) | 170 (597) | .004 |
| Waitlist removal because of death, n (%) | 994 (18.2) | 752 (18.0) | 165 (20.8) | 39 (13.0) | 38 (18.9) | <.001 |
| Waitlist time (d) to death (median, SD) | 465 (915) | 473 (1073) | 308 (892) | 613 (909) | 237 (710) | .001 |
| MELD score at death (mean, SD)b | 25.30 (11.6) | 24.8 (11.5) | 28.1 (12.5) | 30.5 (11.0) | 29.1 (10.8) | <.001 |
| Waitlist removal because of clinical deterioration, n (%) | 430 (7.8) | 313 (7.5) | 80 (10.0) | 21 (7.0) | 16 (7.9) | <.001 |
BMI, body mass index; HCC, hepatocellular carcinoma; HE, hepatic encephalopathy; INR, international normalized ratio for prothrombin time; LT, liver transplantation; MELD, Model for End-Stage Liver Disease; OPTN/UNOS, Organ Procurement Transplant Network/United Network for Organ Sharing; PBC, primary biliary cholangitis; SBP, spontaneous bacterial peritonitis; SD, standard deviation.