Table 2.
Multivariate Cox Regression Analysis Assessing Predictors for Overall Rate of Undergoing LT From Waitlist Registration Among PBC Waitlist Registrants, OPTN/UNOS 2000–2014
| Multivariate HRa |
95% CI |
P value |
|
|---|---|---|---|
| Initial age | 1.00 | 1.00–1.01 | .12 |
| Gender | |||
| Female | Reference | ||
| Male | 1.15 | 1.00–1.32 | .06 |
| Ethnicity | |||
| White | Reference | ||
| Black | 1.03 | 0.85–1.26 | .75 |
| Hispanic | 0.71 | 0.60–0.83 | <.001 |
| Asian | 0.76 | 0.63–1.08 | .13 |
| Other | 0.68 | 0.44–1.05 | .08 |
| Body mass index | 0.99 | 0.98–0.99 | .02 |
| Diabetes | 0.91 | 0.78–1.06 | .22 |
| Initial MELD score | 1.15 | 1.14–1.16 | <.001 |
| Ascites | 1.35 | 1.18–1.52 | .01 |
| Hepatic encephalopathy | |||
| None | Reference | ||
| Moderate | 1.13 | 1.01 −1.26 | .03 |
| Severe | 1.18 | 0.99–1.56 | .23 |
| Portal venous thrombosis | 0.90 | 0.68–1.19 | .45 |
| Spontaneous bacterial | 0.99 | 0.77–1.27 | .93 |
| peritonitis |
CI, confidence interval; HR, hazard ratio; LT, liver transplantation; MELD, Model for End-Stage Liver Disease; OPTN/UNOS, Organ Procurement Transplant Network/United Network for Organ Sharing; PBC, primary biliary cholangitis.
a
Additionally adjusted for OPTN/UNOS region of listing.