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. 2020 Jun 1;12(6):e8401. doi: 10.7759/cureus.8401

Table 5. Reported results of stereotactic radiosurgery/stereotactic radiotherapy for paraganglioma (Glomus tumor).

Pts. = patients; Vol. = volume; yr = year; mo = months; GK = Gamma Knife; LINAC = linear accelerator-based system; SRS = stereotactic radiosurgery; SRT = stereotactic radiotherapy; PFS = progression-free survival; FU = follow-up.

Author, Year Modality No. of Pts. Median Vol. (ml) Mean Margin Dose (Gy) Local Control (%) Survival (%) Side Effects
Hafez et al., 2016 [33] GK 22 7.3 (mean) (2.8-19.4) 14.7 SRS (12-16) 95.5 (5 yr, PFS), 95.5 (7 yr) 95.5 (5 yr), 95.5 (7 yr) ND
Dobberpuhl et al., 2016 [34] GK 12 up to 4.5 cm in diameter (12-18) 100 (FU, 13-96 mo) 100 (FU, 13-96 mo) none
Winford et al., 2017 [35] GK 33 5.8 (mean) (0.9-11.4) 13.2 SRS (11-15) 95 (5 yr, PFS), 75 (10 yr) 100 (FU, 5.5-141 mo) 3.7%
Kida et al., (ours), 2000 [4] GK 4 11.6 (7.5-23.5) 15.5 SRS (15-16) 100 (5 yr) 100 (5 yr) none
Tripathi et al., 2019 [36] GK SRS/SRT 10 29.9 (mean) (9.95-47.6) (16-22 SRS, 22.4/2 fx. or 22.9/3 fx.) 100 (FU, 12-78 mo) 100 (FU, 12-78 mo) 1.8%
Gigliotti et al., 2018 [37] LINAC SRS/SRT 16 11.7 (PTV) (15 SRS, 21/3 fx., or 25-27.5/5 fx.) 88 (5 yr) 100 (FU, 55-87 mo) 6%