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. 2020 Jul 2;15(7):e0235553. doi: 10.1371/journal.pone.0235553

Fig 1. Opg deficiency tends to suppress AngII-induced aortic aneurysms.

Fig 1

(A) Aortas of AngII-infused ApoE-/-Opg+/+ and ApoE-/-Opg-/- mice were categorized into three groups based on diameter and the presence of visible hematoma (No Aneurysm, Aneurysm, and Dissection groups). Scale bars indicate 1 mm. (B) External diameter of the SRA in AngII-infused ApoE-/-Opg+/+ (gray, n = 16) and ApoE-/-Opg-/- (white, n = 16) mice. All measurements are shown as box plots and each measurement is shown as a white circle (No Aneurysm), gray triangle (Aneurysm), or black cross (Dissection). (C) The incidence (%) of aortic aneurysms is shown for No Aneurysm (white), Aneurysm (gray), and Dissection (black) groups. Statistical significance: p<0.05.