Skip to main content
. 2020 Jul 2;15(7):e0235512. doi: 10.1371/journal.pone.0235512

Table 3. Allelic frequencies reported in Latin American population.

Country Trait Cases Controls Reference
Sample size S L Sample size S L
Colombia ASD 105 0.59 0.41 171 0.52 0.48 Present study
Colombia Bipolar disorder 103 0.49 0.51 112 0.53 0.47 [Ospina-Duque et al., 2000] [37]
Colombia MDD 68 0.49 0.51 68 0.45 0.55 [Pérez-Olmos, et al., 2016] [38]
Colombia Bipolar disorder 133 0.55 0.45 120 0.59 0.41 [Ramos, et al., 2012] [39]
Colombia MDD 59 0.53 0.47 59 0.44 0.56 [Escobar, et al., 2011] [40]
Mexico Obsessive‐compulsive disorder 115 0.58 0.42 136 0.52 0.48 [Camarena et al., 2001] [41]
Mexico MDD 104 0.52 0.48 335 0.60 0.40 [Peralta-Leal et al., 2012] [42]
Mexico ADHD 78 0.43 0.57 56 0.55 0.45 [Durán-González et al., 2018] [43]
Mexico MDD and suicide attempt 200 0.63 0.37 233 0.51 0.49 [Sarmiento-Hernandez et al., 2019] [44]
Argentina MDD 95 0.51 0.49 107 0.47 0.53 [Cajal et al., 2012] [45]
Brazil Bipolar Disorder 167 0.37 0.63 184 0.36 0.64 [Neves et al., 2008] [46]
Brazil Schizophrenia* 39 0.42 0.58 98 0.38 0.62 [Mendes De Oliveira et al., 1998] [47]
Brazil Bipolar Disorder* 47 0.40 0.60 98 0.38 0.62 [Mendes De Oliveira et al., 1998] [47]
Brazil Dysthimia~ 62 0.43 0.57 197 0.38 0.62 [Oliveira et al., 2000] [48]
Brazil Bipolar disorder~ 64 0.38 0.62 197 0.38 0.62 [Oliveira et al., 2000] [48]
Brazil MDD~ 66 0.42 0.58 197 0.38 0.62 [Oliveira et al., 2000] [48]
Brazil Anxiety 129 0.43 0.57 96 0.43 0.57 [Bortoluzzi et al., 2014] [49]
Brazil Suicide in depressed patients 84 0.48 0.52 152 0.44 0.56 [Segal, et al, 2006] [50]
Brazil Epilepsy 175 0.47 0.53 155 0.45 0.55 [Schenkel et al., 2011] [51]
Brazil ASD 151 0.44 0.56 179 0.45 0.55 [Longo, et al, 2009] [52]
Brazil Schizophrenia—Bipolar disorder 99 0.40 0.60 60 0.47 0.53 [Krelling et al., 2008] [53]
Brazil Obsessive‐compulsive disorder 78 0.54 0.46 202 0.52 0.48 [Meira-Lima et al., 2004] [54]

ASD: Autism Spectrum Disorder, MDD: Major Depressive Disorder, ADHD: Attention Deficit Hyperactivity Disorder.

*Two traits evaluated independently but using the same control group,

~Three traits evaluated independently but using the same control group