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Comparison of Receiver Operating Characteristic Curves for Serum AFP, let-7a-1, and Combination of both in HCC Versus Cirrhosis Group
| Variable | Cut off | Sensitivity | Specificity | PVP | PVN | DA |
|---|---|---|---|---|---|---|
| AFP | 132 ng/ml | 82.5% | 100% | 100% | 74.1% | 88.3% |
| Let-7a-1 | ≤ 3.0 | 70% | 82.5% | 66.7% | 84.6% | 78.3% |
| AFP + Let-7a-1 |
One positive of two | 95% | 100% | 100% | 90.9% | 96.6% |
PVP, Predictive value of positive; PVN, Predictive value of negative; DA, Diagnostic accuracy.
