Table 3.
Distribution of the Studied Familial Breast Cancer Patients According to Demographic and Clinical Parameters (N = 80)
| No. | % | |
|---|---|---|
| Age of first presentation (years) | 48.31 ± 10.97 | |
| ≤50 | 44 | 55.00 |
| >50 | 36 | 45.00 |
| No. of affected family members | ||
| One relative | 57 | 71.25 |
| Two relatives | 14 | 17.50 |
| Three relatives | 9 | 11.25 |
| Different types of cancers in the relatives of FBC patients | ||
| Breast | 101 | 90.18 |
| Others | 11 | 9.82 |
| Menstrual history | ||
| Premenopausal | 46 | 57.50 |
| Menopausal | 34 | 42.50 |
| Marital status | ||
| Not married | 10 | 12.50 |
| Married | 70 | 87.50 |
| Parity | ||
| Nulliparous | 11 | 13.75 |
| Multiparous | 69 | 86.25 |
| Breast feeding | 69 | 86.25 |
| Clinical presentation | ||
| Breast lump | 70 | 86.42 |
| Others | 11 | 13.58 |
| Mammography | ||
| BIRADS IV | 35 | 43.75 |
| BIRADS V | 35 | 43.75 |
| Others | 10 | 12.50 |
| Histopathological type | ||
| IDC | 67 | 83.75 |
| Others(ILC,DCIS and mixed mucinous) | 13 | 16.25 |
| TNM Stage | ||
| II | 37 | 46.25 |
| III | 22 | 27.50 |
| IV | 11 | 13.75 |
| Others (stage 0 and I) | 10 | 12.50 |
| Non-metastasis | 69 | 86.25 |
| Metastasis | 11 | 13.75 |
| Hormone receptor and HER2 status | ||
| ER+ PR+ HER2-ve (Luminal A) | 51 | 63.75 |
| ER+ PR+ HER2+ve (Triple positive) | 10 | 12.50 |
| HER2+ve (HER2 enriched) | 10 | 12.50 |
| ER- PR- HER2-ve (Triple negative) | 9 | 11.25 |
| Carrier status of BRCA1 5382insC mutation | ||
| Non-carrier | 76 | 95 |
| Carrier | 4 | 5 |
IDC, Infiltrating ductal carcinoma; ILC, Invasive lobular carcinoma; DCIS, Ductal carcinoma in situ