Table 2.

Comparison between Expression Parameters of CDK4 and STAT3 in Subgroups of Urothelial Carcinoma (UC) as Regards to Tumor Grade, Papillary Pattern, Muscle Invasion and Bilharzial Association

Papillary pattern
Negative	Mean	25	25	66.87	163.12
	N	16	16	16	16
	SEM	8.8	8.8	6.63	24.32
positive	Mean	15.48	17.41	25.32**	49.03**
	N	31	31	31	31
	SEM	3.73	3.87	4.48	11.61
Grade( Low / High)		CDK4 percent	CDK4 score	STAT3 percent	STAT3 score
high	Mean	12	12	40.33	96.66
	N	16	16	16	16
	SEM	4.82	4.82	6.54	19.25
low	Mean	18.7	20.64	26.29	48.70*
	N	31	31	31	31
	SEM	3.95	4.03	4.3	10.48
Muscle invasion
NMIBC	Mean	19.09	20.9	27.72	50.3
	N	33	33	33	33
	SEM	3.87	3.94	4.16	9.96
MIBC	Mean	11.07	11.07	39.64	98.21 *
	N	14	14	14	14
	SEM	4.96	4.96	7	20.57
Bilharzial association
Negative	Mean	14.21	15.26	32.36	71.05
	N	41	41	41	41
	SEM	3.8	3.87	5.05	14.23
positive	Mean	11.81	11.81	17.72	34.09
	N	6	6	6	6
	SEM	7.87	7.87	7.09	14.57

*, Significant difference between comparable groups (p<0.05); **, High Significant difference between comparable groups (p<0.01)