Table 4.

Genotypic Frequencies of TNF-α (-308) and TNF-β (+ 252), Genotype and Estrogen Receptor Status, Progesterone Receptor status, Herception Receptor Status

Genotype	Total (n=150) (%)	Estrogen Receptor Positive (n=67) (%)	Estrogen Receptor Negative (n=83) (%)	p value	OR(95%CI)
TNF-α (-308) (rs1800629G>A)
GG	68 (45.3)	28 (41.7)	40 (48.1)	0.5099	0.77 (0.40-1.47)
GA	73 (48.6)	34 (50.7)	39 (46.9)	0.7428	1.16(0.61-2.21)
AA	9 (6.0)	5 (7.4)	4 (4.8)	0.5137	1.59(0.41-6.18)
TNF-β (+252) (rs361525 A>G)
AA	86 (57.3)	38 (56.7)	48 (57.9)	1	0.95(0.49-1.83)
AG	56 (37.4)	27 (40.3)	29 (34.9)	0.6107	1.25 (0.64-2.44)
GG	8 (5.3)	2 (3.0)	6 (7.2)	0.2987	0.39 (0.07-2.02)
Genotype	Total (n=150) (%)	Progesterone Receptor Positive (n=71) (%)	Progesterone Receptor Negative (n=79) (%)	p value	OR(95%CI)
TNF-α (-308) (rs1800629G>A)
GG	68 (45.3)	36 (50.7)	32 (40.5)	0.2511	1.51 (0.79-2.88)
GA	73 (48.6)	31 (43.6)	42 (53.1)	0.2571	0.68 (0.35-1.30)
AA	9 (6.0)	4 (5.6)	5 (6.3)	1	0.88 (0.22-3.42)
TNF-β (+252) (rs361525 A>G)
AA	86 (57.3)	45 (63.4)	41 (52.0)	0.1868	1.60 (0.83-3.08)
AG	56 (37.4)	23 (32.4)	33 (41.7)	0.2432	0.66 (0.34-1.30)
GG	8 (5.3)	3 (4.2)	5 (6.3)	0.7223	0.65 (0.15-2.83)
Genotype	Total (n=150) (%)	Herceptin Receptor Positive (n=82) (%)	Herceptin Receptor Negative (n=68) (%)	p value	OR (95%CI)
TNF-α (-308) (rs1800629G>A)
GG	68 (45.3)	37 (45.1)	31 (45.5)	1	0.98 (0.51-1.87)
GA	73 (48.6)	41 (50)	32 (47.0)	0.7451	1.12 (0.59-2.14)
AA	9 (6.0)	4 (4.9)	5 (7.3)	0.7321	0.64 (0.16-2.50)
TNF-β (+252) (rs361525 A>G)
AA	86 (57.3)	49 (59.8)	37 (54.4)	0.6191	1.24 (0.64-2.38)
AG	56 (37.4)	28 (34.1)	28 (41.2)	0.4005	0.74 (0.38-1.44)
GG	8 (5.3)	5 (6.1)	3 (4.4)	0.7291	1.40 (0.32-6.11)