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. 2020 Jun 4;2(Suppl 1):1–10. doi: 10.1093/noajnl/vdaa070

Table 2.

Multivariable Logistic Regression Results of Patient and Treatment Factors Associated With Odds of Longer-Term Survival (>3 years) After Diagnosis With Glioblastoma, NCDB 2005–2015

Univariable OR (95% CI) P Multivariable OR (95% CI) P
Age (years)
 70 Reference Reference
 <60 5.58 (5.17–6.02) <.0001 4.46 (4.11–4.84) <.0001
 60–70 2.60 (2.39–2.82) <.0001 2.22 (2.04–2.43) <.0001
Sex
 Male Reference Reference
 Female 1.15 (1.10–1.2) <.0001 1.19 (1.19–1.31) <.0001
Race
 White Reference Reference
 Black 1.26 (1.15–1.38) <.0001 1.19 (1.08–1.32) .0008
 Others 1.69 (1.53–1.87) <.0001 1.58 (1.40–1.79) <.0001
Ethnicity
 Non-Hispanic Reference Reference
 Hispanic 1.56 (1.43–1.72) <.0001 1.45 (1.31–1.60) <.0001
Charlson/Deyo score
 ≥3 Reference Reference
 0 2.49 (2.11–2.93) <.0001 1.92 (1.61–2.28) <.0001
 1 1.53 (1.29–1.82) <.0001 1.42 (1.18–1.71) .0001
 2 1.28 (1.06–1.55) .009 1.17 (0.96–1.44) .1162
Tumor location
 Infratentorial Reference Reference
 Supratentorial 1.28 (1.01–1.62) .0438 1.58 (1.21–2.06) .0007
 Others 0.92 (0.72–1.17) .5142 1.22 (0.93–1.59) .1513
Treatment type
 Radiation only Reference Reference
 Chemotherapy only 1.89 (1.09–3.29) .024 1.40 (0.79–2.47) .2506
 Radiation + chemotherapy 2.59 (1.88–3.58) <.0001 1.88 (1.36–2.61) .0001
 Surgery only 2.75 (2.00–3.78) <.0001 2.30 (1.66–3.17) <.0001
 Surgery + radiation 3.27 (2.35–4.54) <.0001 2.57 (1.84–3.58) <.0001
 Surgery + chemotherapy 5.00 (3.56–7.01) <.0001 3.73 (2.65–5.25) <.0001
 All modalities 7.65 (5.61–10.43) <.0001 4.89 (3.58 - 6.68) <.0001

OR, odds ratio; 95% CI, 95% confidence interval.

All modalities: surgery + radiotherapy + chemotherapy.