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PTGDR in recipient mice is required for development of EAE. (A) Protocol for generating Th17 CD4 T cells for adoptive transfer model. (B) Disease scores after adoptive transfer of B6 or PTGDR−/− CD4 T cells into B6 or PTGDR−/- recipients. (C) Dynamics of donor T cell accumulation in lymphoid tissues. (B and C) n = 5, data are shown as mean ± SEM and are representative of 3 independent experiments. *p < 0.05.
