Table 2.
Virion-associated proteins of arterivirusesa
| Protein | sizeb | ORF | mRNA | (putative) function(s) |
|---|---|---|---|---|
| Ed | 67–70 | 2a/2bc | 2d | small integral envelope protein |
| GP2 | 227–249 | 2b/2ac | 2d | minor glycoprotein, part of GP2/GP3/GP4 heterotrimer |
| GP3 | 163–265 | 3 | 3 | minor glycoprotein, part of GP2/GP3/GP4 heterotrimer |
| GP4 | 152–183 | 4 | 4 | minor glycoprotein, part of GP2/GP3/GP4 heterotrimer |
| GP5 | 199–255 | 5 | 5 | major glycoprotein, carries main determinants for neutralization, part of GP5/M heterodimer |
| M | 162–173 | 6 | 6 | integral (triple-spanning) membrane protein, part of GP5/M heterodimer |
| N | 110–128 | 7 | 7 | nucleocapsid protein, partially localizes to the nucleus of infected cells |
a
Based on the genome organization of EAV, PRRSV and LDV
b
in aa
c
in PRRSV
d
sgRNA2 is assumed to be functionally bicistronic