Skip to main content
. Author manuscript; available in PMC: 2021 Jul 3.
Published in final edited form as: Mol Psychiatry. 2020 Jan 3;26(8):3795–3805. doi: 10.1038/s41380-019-0640-9

Figure 4. The effects of the DHCR24 rs588709-G on lipoprotein particle size, apolipoproteins, cholesterol, triglycerides, phospholipids, amino acids and glycoprotein acetylation.

Figure 4.

The metabolic effects of the DHCR24 rs588709-G were evaluated in 931 SYS adolescents in linear models, in which metabolite concentrations served as outcomes and DHCR24 rs588709-G allele count (0, 1, 2) as predictor. Metabolite concentrations were adjusted for age, sex, and family relatedness, and rank transformed to normality. Error bars indicate 95% confidence intervals. Statistical significance was considered at p<0.002 (0.05/29) to account for testing of 29 independent metabolic measures.

VLDL, very-low-density lipoprotein; LDL, low-density lipoprotein; HDL, high-density lipoprotein; ApoB, apolipoprotein B; ApoA-I, apolipoprotein A-I; C, cholesterol; TG, triglyceride; PG, phosphoglyceride; PC, phosphatidycholine; SM, sphingomyelin; GlycA, glycoprotein acetylation.