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. Author manuscript; available in PMC: 2021 Sep 2.
Published in final edited form as: Hepatology. 2020 Sep 2;72(3):1085–1101. doi: 10.1002/hep.31096

Figure 3. The serial passagability of liver cancer PDX models.

Figure 3.

A. This shows the passagability of PDXs generated in three types of recipients. Fisher’s exact t-test was used for statistical analysis.

B. Time required for each PDX model to engraft and passage. Once engrafted, tumors were passaged into additional NSG mice to expand the PDX lines. HCC-HS84 was generated from NSG mice. HCC-HS119 was generated from FRG mice. All other lines were generated from NSG mice that had undergone PHx.

C. Engraftment time for frozen and thawed PDX tumors. CCA-HS127, CCA-HS131, HCC-HS84, HCC-HS119, HCC-HS157, and CCA-HB163 can be expanded.