Table 3.

Between-survey comparisons of differences in any nonmedical cannabis use, frequent nonmedical use, and DSM-IV cannabis use disorder by pain status among U.S. adults, 2012–2013 and 2001–2002^a

Cannabis Outcome	Difference in Risk Differences, 2012–2013 Versus 2001–2002		Ratio of Risk Ratios, 2012–2013 Versus 2001–2002
	Difference in Risk Differences	95% CIb	Ratio of Risk Ratios	95% CIc
Any nonmedical used	1.99	0.69, 3.29	1.00	0.82, 1.24
Frequent nonmedical usee	1.35	0.47, 2.23	1.20	0.85, 1.83
DSM-IV cannabis use disorder	1.02	0.18, 1.86	1.16	0.80, 1.83

^aData are from the 2001–2002 National Epidemiologic survey on Alcohol and Related conditions (NESARC) survey and the 2012–2013 NESARC-III survey. All estimates are adjusted for sociodemographic covariates (age, gender, race/ethnicity, education level, marital status, and family income) and pain-by-covariate interactions.

^bAdditive interaction: differences in risk differences whose 95% confidence intervals do not include 0.0 are statistically significant at p<0.05 and are in boldface.

^cMultiplicative interaction: ratios of risk ratios whose 95% confidence intervals do not include 1.0 are statistically significant at p<0.05; none shown are significant.

^dNonmedical use was defined as cannabis use without a prescription or other than prescribed, for example, to get high.

^eFrequent use was defined as cannabis use at least three times a week.