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. 2020 Jul 3;28(3):475–485.e5. doi: 10.1016/j.chom.2020.06.021

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Human Immune Serum Neutralization of SARS-CoV-2 and VSV-SARS-CoV-2-S_Δ21

(A and B) Representative neutralization curves of serum from SARS-CoV-2-infected donors with low, medium, and high inhibitory activity against SARS-CoV-2 (A) or VSV-SARS-CoV-2-S_Δ21 (B) (n = 2 and 2, respectively). Error bars in (A) and (B) represent the standard error of the mean.

(C) EC₅₀ values of all human serum tested for neutralization of SARS-CoV-2 and VSV-SARS-CoV-2-S_Δ21. Differences in the geometric mean or median titers were 3.0-fold between FRNT and GRNT assays. See also Figure S4.