Skip to main content
. 2020 Jun 26;21:e00892. doi: 10.1016/j.idcr.2020.e00892

Table 1.

Literature review of tuberculosis with ruxolitinib treatment in patients with primary myelofibrosis.

Year/reference Country Age /sex Culture Diagnosis (abnormality) Timing of infection after the start of ruxolitinib IGRA before ruxolitinib IGRA after diagnosis of TB Treatment for LTBI Other risk of tuberculosis Ruxolitinib therapy after diagnosis of infection Outcome
Branco (2016) [5] Born in Algeria but living in France 78/F Cervical lymph node Disseminated (cervical lymph node, T4–T5 spinal disc) 1.5 years NA Positive None Diabetes Continued Alive
Shamil (2015) [6] UK 78/F Cervical lymph node Disseminated (cervical lymph node, lung) Unspecified NA NA None None Discontinued Alive
Keizer (2015) [7] Netherland 72/M N/A Disseminated(N/A) 5 months Not performed NA N/A N/A Discontinued dead
Keizer (2015) [7] Netherland 68/M N/A Pulmonary 4 weeks Not performed NA N/A N/A Discontinued dead
Chen (2015) [9] Taiwan 82/M Sputum Pulmonary 2 months NA NA None PSL 10 mg Discontinued Alive
Palandri (2015) [10] Italy 65/F Lymph node Extrapulmonary (subaxillary lymph nodes) 4 months Not performed Negative None none Discontinued Alive
Hopman (2014) [11] Emigrated from Vietnam to the United States 62/M BALF, blood Disseminated (lung, lymph node) 7 weeks NA NA none none Discontinued Alive
Colomba (2012) [12] Italy Unspecified/M Inguinal lymph node, sputum Disseminated (inguinal lymph node, lung) 2 months NA Positive None none Unspecified Unspecified
Panda (2016) [13] India 35/M Right psoas abscess Disseminated (psoas muscle, para-aortic lymph node, lung) 2 years NA NA None hydroxyurea 6 weeks continued, discontinued Alive
Abidi (2016) [14] India 69/M Cervical lymph node Disseminated (lung, cervical lymph node) 3 weeks NA Positive None None Discontinued Alive
Tsukamoto (2017) [8] Japan 73/M Sputum, gastric lavage fluid, blood, and urine Disseminated (lung) 6 months NA Positive None PSL 5 mg Discontinued dead
Lescuyer et al. (2019) [15] France 73/M Cerebral biopsy Disseminated (lung, brain) 5 months NA Positive None None Discontinued dead
Current Japan 80/M Sputum, skin abscess Disseminated (skin abscess, lung, spine) 10 months Not performed Positive None PSL 5 mg 4 months continued, discontinued dead

NA: not available; there was no relevant information in the manuscript.