Skip to main content
. 2019 Nov 1;10(6):1106–1121. doi: 10.1016/j.apsb.2019.10.011

Figure 7.

Figure 7

In vivo anti-tumor efficiency. (A) Biodistributions in A549 xenograft tumor-bearing nude mice tissues at 1, 6, 12 and 24 h after intravenous injection of free Pt–CUR and Pt–CUR@PSPPN. (B) Tumor growth curves during treatment. Mice were given tail vein injection of different drug formulations including free CDDP, free CUR, a combo of free drugs, free Pt–CUR as well as Pt–CUR@PPPN, Pt–CUR@PSPN, and Pt–CUR@PSPPN on day 9, 12, 15 and 18 after tumor inoculation. (C) Image and (D) weight of excised tumors at the end of the experiment (day 28 after tumor inoculation). Data are expressed as mean ± SD (n = 5). *P < 0.05, **P < 0.01.