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. 2020 Apr 29;21(7):e49443. doi: 10.15252/embr.201949443

Figure 5. Mettl5 is required for fly orientation.

Figure 5

  1. Cartoon depicting the experiment with the main components of the setup showing the arena in white, the visual landmarks as black stripes and the camera to record the fly (left, from Ref. 37), and cartoon showing the normal behavior of a WT fly in the arena. The black rectangles represent the visual landmarks and the red arrow the main trajectory undertaken by WT flies relative to the position of the landmarks (right).
  2. Representative trajectories of WT and Mettl5 mutant flies analyzed by Buridan's paradigm. The blue lines indicate when the fly stops and changes direction.
  3. Orientation evaluated with the help of Buridan's paradigm for Mettl5 mutant flies. Orientation was measured as the angular deviation from the straight path needed to move from one landmark to another in the arena. Number of flies tested per genotype: 30. Mean ± standard deviation. Shapiro–Wilk test was used to test for normal distribution in each group. Normally distributed groups were tested by t‐test. Due to multiple comparison, Bonferroni correction was applied (*P < 0.05; ****P < 0.0001).