Figure EV4. MALT1 inhibition reduces proinflammatory gene expression in ears of ieCARD14^E138A mice.

mRNA expression levels of the indicated genes in ears relative to reference genes (Hprt1 and Tbp). Each symbol represents one mouse; the line represents the mean value (n ≥ 3). Statistics: Differences between ieCARD14^E138A + vehicle and ieCARD14^E138A + MALT1 inhibitor groups were determined using a Mann–Whitney U‐test (*P < 0.05, **P < 0.01). WT = K14creER^Tg/+ Rosa26^+/+, ieCARD14^E138A = K14creER^Tg/+ Rosa26^{LSL‐CARD14‐E138A/+}.