Table 1.
Expression of RICTOR and p-AKT (Ser473) in ESCC and normal esophageal tissues.
| Tissue type | n | RICTOR |
p-AKT (Ser473) |
||||
|---|---|---|---|---|---|---|---|
| Positive (%) | Negative (%) | P | Positive (%) | Negative (%) | P | ||
| Normal | 150 | 27 (18.0) | 123 (82.0) | 0.000 | 45 (30.0) | 105 (70.0) | 0.000 |
| ESCC | 150 | 92 (61.3) | 58 (38.7) | 98 (65.3) | 52 (34.7) | ||
To explore the activated state of mTORC2/AKT in ESCC and their clinical significance, the expressions of RICTOR and p-AKT (Ser473) in 150 ESCC and normal esophageal tissues were examined by immunohistochemistry. The expressions of RICTOR and p-AKT (Ser473) protein were significantly higher in ESCC tissues than that in normal esophageal tissues and had statistically significant differences (P < 0.05).