Table 1.
Articles that studied the urinary microbiome in healthy individuals, or healthy controls in case-control studies
| Study | No. | Sex | Age | Urine collection | Microbiome |
|---|---|---|---|---|---|
| Siddiqui et al. [2] (2011) | 8 | F | 27-67 yr | CCU | Lactobacillus, Prevotella, Gardnerella, Peptoniphilus, Dialister, Finegoldia, Anaerococcus, Allisonella, Streptococcus, Staphylococcus |
| Wolfe et al. [5] (2012) | 12 | F | NA | CCU, TUC, SPA | Lactobacillus, Actinobaculum, Aerococcus, Anaerococcus, Atopobium, Burkholderia, Corynebacterium, Gardnerella, Prevotella, Ralstonia, Sneathia, Staphylococcus, Streptococcus, Veillonella |
| Fouts et al. [3] (2012) | 11 | M | 24-50 yr | MSU | Corynebacterium, Staphylococcus, Streptococcus, Lactobacillus, Gardnerella, Veillonella |
| 15 | F | 22-51 yr | Lactobacillus, Corynebacterium, Staphylococcus, Streptococcus, Prevotella | ||
| Nelson et al. [4] (2012) | 18 | M | 14-17 yr | FCU | Corynebacterium, Lactobacillus, Staphylococcus, Gardnerella, Streptococcus, Anaerococcus, Veillonella, Prevotella, Escherichia |
| Lewis et al. [6] (2013) | 6 | M | 39-83 yr | CCU | Firmicutes |
| 10 | F | 26-90 yr | Firmicutes, Actinobacteria, Bacteroidetes | ||
| Hilt et al. [7] (2014) | 24 | F | NA | TUC | Lactobacillus, Corynebacterium, Streptococcus, Actinomyces, Staphylococcus, Aerococcus, Gardnerella, Bifidobacterium, Actinobaculum |
| Pearce et al. [8] (2014) | 58 | F | 35-65 yr | TUC | Lactobacillus, Gardnerella, Corynebacterium, Enterobacteriaceae, Anaerococcus, Bifidobacterium, Streptococcus, Staphylococcus, Sneathia, Peptoniphilus, Atopobium, Rhodanobacter, Trueperella, Alloscardovia, Veillonella |
| Karstens et al. [9] (2016) | 10 | F | 58 (mean) | TUC | Anoxybacillus, Lactobacillus, Prevotella, Gardnerella, Arthrobacter, Escherichia, Shigella |
| Thomas-White et al. [10] (2016) | 60 | F | 35-65 yr | TUC | Lactobacillus, Gardnerella, Staphylococcus, Streptococcus, Enterococcus, Bifidobacterium, Atopobium, Enterobacteriaceae |
| Wu et al. [15] (2017) | 25 | F | 26 (mean) | TUC | Lactobacillaceae, Prevotellaceae, Enterobacteriaceae, Veillonellaceae, Tissierellaceae, Bifidobacteriales |
| Gottschick et al. [12] (2017) | 49 | F | 19-62 yr | MSU | Lactobacillus crispatus |
| Abernethy et al. [11] (2017) | 20 | F | 28-43 yr | TUC | Lactobacillus acidophilus |
| Wang et al. [14] (2017) | 21 | F | 43 (mean) | MSU | Lactobacillus, Varibaculum, Porphyromonas, Prevotella, Bacteroides |
| Rani et al. [13] (2017) | 5 | F | 27-63 yr | MSU | Proteobacteria, Firmicutes, Actinobacteria, Bacteroidetes |
| 3 | M | ||||
| Wu et al. [18] (2018) | 18 | M | 55.5 (mean) | MSU | Escherichia-Shigella, Staphylococcus, Streptococcus, Aeromonas, Acinetobacter, Bacteroides, Lactobacillus |
| Komesu et al. [17] (2018) | 84 | F | 53 (mean) | TUC | Lactobacillus, Gardnerella, Tepidimonas, Prevotella |
| Bucevic Popovic et al. [16] (2018) | 19 | M | 61-82 yr | MSU | Firmicutes, Actinobacteria, Bacteroidetes, Proteobacteria |
| Meriwether et al. [21] (2019) | 18 | F | 33.7 (mean) | MSU | Lactobacillus, Prevotella |
| Bresler et al. [19] (2019) | 20 | F | 48 (mean) | MSU | Lactobacillus |
| Kassiri et al. [20] (2019) | 10 | M | 3 mo-8 yr | TUC | Staphylococcus, Varibaculum, Peptoniphilus, Actinobaculum |
| Xie et al. [23] (2020) | 21 | M | 44.2 (mean) | NA | Acinetobacter, Prevotella, Oscillospira, Parabacteroides, Fusobacterium |
| Liu et al. [22] (2020) | 9 | M | 58.9 (mean) | TUC | Gardnerella, Pontibacter, Sphingomonas, Prevotella, Propionibacterium |
| 3 | F |
CCU, clean catch urine; TUC, transurethral catheter; SPA, suprapubic aspirate; MSU, midstream urine; FCU, first catch urine; NA, not available.