TABLE 2.
Comparison of the features in human and ovine fetal SFK.
Characteristics | Congenital SFK |
|||||
Children | Age at onset | References | Ovine (males only) | Age at measurement | References | |
Elevated blood pressure | √ | Mean 4.9 years | Westland et al. (2013a) | √ (7–15 mmHg) | 6 months | Singh et al. (2010) |
Reduced GFR | √ | Mean 6.4 years | Westland et al. (2013a) | √ (30% decrease) | 6 months | Singh et al. (2010) |
Albuminuria | √ | Mean 9.8 years | Westland et al. (2013a) | √ | 6 months | Singh et al. (2009) |
Kidney hypertrophy | √ | 20–36 weeks gestation | Van Vuuren et al. (2012b) | √ | 130 days gestation | Douglas-Denton et al. (2002) |
GFR, glomerular filtration rate.