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. 2020 Jun 26;11:725. doi: 10.3389/fphys.2020.00725

TABLE 2.

Comparison of the features in human and ovine fetal SFK.

Characteristics Congenital SFK
Children Age at onset References Ovine (males only) Age at measurement References
Elevated blood pressure Mean 4.9 years Westland et al. (2013a) √ (7–15 mmHg) 6 months Singh et al. (2010)
Reduced GFR Mean 6.4 years Westland et al. (2013a) √ (30% decrease) 6 months Singh et al. (2010)
Albuminuria Mean 9.8 years Westland et al. (2013a) 6 months Singh et al. (2009)
Kidney hypertrophy 20–36 weeks gestation Van Vuuren et al. (2012b) 130 days gestation Douglas-Denton et al. (2002)

GFR, glomerular filtration rate.