Figure 5.

GPR110 overexpression in H1299 cells significantly promoted tumor growth in the nude mice tumor xenograft model. (A) Representative photographs of the nude mice tumor xenograft, showing the mice subcutaneously injected with H1299 cells with GPR110 overexpression (n=6) and the control group (n=6). (B) Tumor nodules extracted from the nude mice tumor xenograft model: vaccinal tumor tissue masses from mice subcutaneously injected with H1299 cells with GPR110 overexpression and the control group. Tumor volume was quantified and statistical analysis was carried out. The values are presented as mean ± SD. *, P<0.05. (C) H&E staining of tumor sections and immunohistochemical staining of Ki-67 in the tumor area (200×), scale bar, 50 µm. *, P<0.05.