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. 2020 Jun;8(12):757. doi: 10.21037/atm-20-4258

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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The effects of eriocitrin on the Nrf2/HO-1 /NQO1/NF-κB signaling pathway in rats with cerebral I/R. (A) The results of ELISA to examine protein expression. (B) The ratio of p-Nrf2 to Nrf2. (C) The ratio of p-P65 to P65. (D) The expression levels of NQO1 and HO-1. **, P<0.01 vs. control group; ^#, P<0.05 vs. cerebral I/R group; ^##, P<0.01 vs. cerebral I/R group. Nrf2, nuclear factor erythroid 2-related factor; HO-1, heme-oxygenase-1; NQO1, quinine oxidoreductase; NF-κB, nuclear factor-κB; I/R, ischemia reperfusion; ELISA, enzyme-linked immunosorbent assay; p-Nrf2, phosphorylation of Nrf2.