Table 3. Correlational Coefficient Between Indoor Environmental and Dry Eye Metrics Taken During Aerocet Count Measurementa.
| Metric | Temperature, oC | Humidity, % | No. of particles >0.5 μm/ft3 of air, loge | No. of particles >5 μm/ft3 of air, loge | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pearson r | P value | Spearman ρ | P value | Pearson r | P value | Spearman ρ | P value | Pearson r | P value | Spearman ρ | P value | Pearson r | P value | Spearman ρ | P value | |
| Symptoms | ||||||||||||||||
| DEQ-5 | −0.06 | .64 | −0.12 | .33 | 0.11 | .34 | 0.12 | .30 | −0.03 | .76 | −0.01 | .92 | 0.19 | .11 | 0.14 | .25 |
| OSDI | 0.21 | .07 | 0.15 | .22 | 0.30 | .01 | 0.23 | .05 | 0.13 | .27 | 0.05 | .70 | 0.26 | .03 | 0.25 | .04 |
| Mean pain intensity in 1 wk | 0.01 | .96 | −0.07 | .56 | 0.20 | .09 | 0.21 | .08 | 0.03 | .79 | −0.03 | .81 | 0.17 | .15 | 0.13 | .30 |
| NPSI-E | 0.05 | .67 | −0.03 | .82 | 0.17 | .14 | 0.20 | .10 | −0.03 | .83 | −0.19 | .10 | 0.14 | .24 | 0.06 | .62 |
| Evoked pain to wind | −0.09 | .43 | −0.10 | .41 | 0.05 | .67 | 0.06 | .64 | −0.20 | .07 | −0.24 | .04 | 0.07 | .57 | 0.04 | .77 |
| Evoked pain to light | 0.04 | .71 | 0.06 | .61 | 0.10 | .39 | 0.15 | .22 | −0.10 | .37 | −0.19 | .11 | 0.04 | .77 | −0.08 | .52 |
| Signsb | ||||||||||||||||
| Osmolarity | 0.08 | .49 | 0.02 | .86 | −0.05 | .69 | −0.13 | .26 | 0.02 | .84 | 0.05 | .65 | 0.09 | .44 | 0.24 | .05 |
| Inflammation | −0.01 | .95 | −0.04 | .74 | 0.32 | .01 | 0.34 | <.001 | 0.03 | .79 | 0.03 | .78 | −0.04 | .76 | −0.15 | .21 |
| Tear breakup time | 0.03 | .82 | −0.07 | .56 | 0.16 | .16 | 0.14 | .24 | −0.18 | .11 | −0.18 | .13 | 0.02 | .89 | −0.03 | .81 |
| Corneal staining | 0.04 | .75 | 0.08 | .52 | 0.11 | .34 | 0.08 | .48 | 0.06 | .63 | −0.04 | .72 | 0.08 | .50 | 0.08 | .52 |
| Schirmer score | −0.20 | .08 | −0.24 | .04 | −0.25 | .03 | −0.26 | .03 | −0.02 | .87 | 0.01 | .90 | 0.04 | .76 | 0.10 | .43 |
| Eyelid vascularity | 0.17 | .14 | 0.21 | .08 | 0.27 | .02 | 0.25 | .03 | 0.01 | .94 | 0.01 | .91 | −0.08 | .49 | −0.14 | .25 |
| Meibomian gland dropout | 0.11 | .35 | 0.18 | .13 | 0.27 | .02 | 0.35 | <.001 | −0.15 | .20 | −0.14 | .24 | −0.06 | .61 | −0.28 | .02 |
| Meibum quality | 0.11 | .35 | 0.12 | .30 | 0.12 | .30 | 0.14 | .23 | −0.03 | .82 | 0.03 | .80 | −0.06 | .61 | −0.01 | .96 |
Abbreviations: DEQ-5, Dry Eye Questionnaire 5; NPSI-E, Neuropathic Pain Symptom Inventory Modified for the Eye; OSDI, Ocular Surface Disease Index.
a
P values were not adjusted for multiple analyses.
b
Values are from the more severely affected eye with higher values for osmolarity, staining, eyelid parameters, and inflammation and lower tear breakup time and Schirmer score.