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. 2020 Jul 3;20:147. doi: 10.1186/s12911-020-01168-0

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Creation of a dictionary cCDE for a CRF. a The ‘Electrolyte Laboratory Tests’ table on a clinical document is provided as an example tabular data-entry document to capture laboratory test results for sodium (Na+) and potassium (K+) along with two clinical evaluation attributes. b We constructed the ‘Electrolyte Laboratory Tests Dictionary’ table by extracting the relevant attributes from the CDEs defined in the ‘Recommended Labs for Stroke’ from the NINDS CDE project. c The dictionary cCDE (DE:47571) consists of six aCDEs that include a variable aCDE (DE:43938) that relates the dictionary cCDE to the dictionary table in Fig. 4b. Two rules for clinical evaluation are presented (http://chmr2.snubi.org:8083/chmr/data_element_view.jsp?id=28445)