Table 7.

Comparison of our proposed semantic types and constraints with the FHIR Questionnaire resource and the other FHIR resources

CDE Semantic Type		FHIR Questionnaire	FHIR other resources
aCDE	Hybrid	No, it does not support the entry of multiple types of data.	Not applicable, there is no restriction on the datatype as it is represented JSON, XML.
	Variable	Yes, it is supported by “coding”.	Yes, it is supported by “coding”.
cCDE	General	Yes, it is supported because the FHIR is following a structured model.	Yes, it is supported because the FHIR is following a structured model.
	Repeated	Yes, it is supported by “repeats”.	Yes, it is supported because the FHIR is allowing repeated representation of the group of items.
	Dictionary	Not applicable, it does not support any value related rule.	Not applicable, it does not support any value related rule.
Constraint	Operated	Allowing only logical operations.	Only resources that have the “operator” are supported (e.g., Observation Resouce).
	Required	Yes, it is supported by “required”.	Yes, it is supported by “required”.
	Dependent	Not applicable, it does not support any value related rule.	Not applicable, it does not support any value related rule
	Ordered	Although not explicit, it is included in the structure.	Only resources that have “sequences” are supported (e.g., Claim Resouce)