Table 3.
Qualitative imaging traits of ICC tumors in 73 patients with assessment of inter-observer agreement
| Observer 1 n (%) |
Observer 2 n (%) |
Kappa | ||
|---|---|---|---|---|
| CT | Biliary obstruction | 27 (52%) | 23 (44%) | 0.69 |
| Capsular bulge/retraction | 31 (60%) | 17 (33%) | 0.50 | |
| Enhancement pattern | 0.68 | |||
| Peripheral progressive | 31 (60%) | 32 (62%) | ||
| Persistent rim | 6 (12%) | 7 (13%) | ||
| Othera | 15 (28%) | 13 (25%) | ||
| Satellite lesionsb | 14 (27%) | 12 (23%) | 0.69 | |
| Vascular involvement | 17 (33%) | 21 (40%) | 0.59 | |
| MRI | Biliary obstruction | 14 (39%) | 14 (39%) | 0.55 |
| Capsular bulge/retraction | 16 (44%) | 7 (19%) | 0.47 | |
| Enhancement pattern | 0.54 | |||
| Peripheral progressive | 24 (66%) | 27 (75%) | ||
| Persistent rim | 6 (17%) | 5 (14%) | ||
| Othera | 6 (17%) | 4 (11%) | ||
| Satellite lesionsb | 7 (19%) | 5 (14%) | 0.60 | |
| Vascular involvement | 13 (36%) | 9 (25%) | 0.57 | |
| ADC (n = 19) | 5 (26%) | 9 (47%) | 0.93 | |
| Hypointense | 14 (74%) | 10 (53%) | ||
| Other# | ||||
| DWI (n = 19) | 0.66 | |||
| Hyperintense | 10 (53%) | 15 (79%) | ||
| Targetoid | 6 (32%) | 4 (21%) | ||
| Otherc | 3 (16%) | 0 (0%) | ||
| HBP (n = 12) | 1.00 | |||
| Hypointense | 12 (100%) | 12 (100%) | ||
| Otherd | 0 (0%) | 0 (0%) | ||
| T2 (n = 36) | 0.29 | |||
| Hyperintense | 21 (58%) | 24 (67%) | ||
| Targetoid | 8 (22%) | 3 (8%) | ||
| Otherc | 7 (19%) | 9 (27%) | ||
a Other enhancement patterns include wash in/wash out, solid whole lesion progressive enhancement, hypovascular or totally necrotic
b For the purpose of statistical analysis, patients with multifocal ICC (n = 4) were included in the group designated as positive for satellite lesions
c Other includes isointense and heterogeneous
d Other includes isointense, hyperintense or targetoid