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. 2020 Jun 26;14:152. doi: 10.3389/fncel.2020.00152

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Copyright © 2020 Zhou, Liu, Han, Zhang, Li, Zhang, Liu, Xia and Tang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pertussis toxin (PTX) reduced poststroke infarct volume and functional deficit. (A) Representative images of triphenyltetrazolium chloride (TTC)-stained brain slice in stroke mice with or without PTX treatment. The infarction area (non-stained region) was quantified in each slice and cumulated as a percentage of total volume. Note PTX-treated animals showed relative less area of infarction. (B) Statistical comparison of infarction volume between stroke mice with or without PTX treatment. (C) Neurological deficit was assessed using Longa score (*P < 0.05).