Table 4.
Validated meQTL-CpG pairs
| meQTL SNP | Chromosome | Associated gene | No. of paired CpGs* |
|---|---|---|---|
| rs301799 | 1 | RERE | 2 |
| rs1890946 | 1 | NRDC | 1 |
| rs72710803 | 1 | AL122019 | 2 |
| rs7585722 | 2 | RNF103-CHMP3 | 2 |
| rs4346585 | 3 | SOCS5P3, ZKSCAN7-AS1 | 3 |
| rs13084037 | 3 | KLHDC8B | 2 |
| rs7624336 | 3 | TKT | 1 |
| rs6783233 | 3 | LOC101926953 | 1 |
| rs7685686 | 4 | HTT | 5 |
| rs34937911 | 4 | SLC30A9 | 1 |
| rs60157091 | 5 | KIF2A | 1 |
| rs200949 | 6 | HIST1H1B | 7 |
| rs7758630 | 6 | LOC107984041 | 1 |
| rs1933802 | 6 | HACE1--[]--LIN28B | 2 |
| rs3823624 | 7 | MAD1L1 | 9 |
| rs2043539 | 7 | TMEM106B | 2 |
| rs7030813 | 9 | PAX5 | 1 |
| rs2670139 | 9 | DENND1A | 1 |
| rs198457 | 11 | - | 4 |
| rs7117514 | 11 | SHANK2 | 1 |
| rs3213572 | 12 | SPPL3 | 1 |
| rs1343605 | 13 | OLFM4--[] | 1 |
| rs4772087 | 13 | STK24 | 1 |
| rs1045430 | 14 | AREL1 | 1 |
| rs62091461 | 18 | RAB27B | 1 |
| rs7241572 | 18 | KCNG2 | 6 |
| rs12624433 | 20 | SLC12A5 | 1 |
| rs5995992 | 22 | RBX1---[]-EP300 | 3 |
*Validation analysis was run by applying lm models between the methylation level and genetic dominant model, adjusting for age and sex The Benjamini-Hochberg multiple-testing adjustment was applied to the p values. A CpG site was paired with the meQTL SNP if the adjusted p value < 0.05
meQTL methylation quantitative trait locus, SNP single nucleotide polymorphism