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. 2020 Jul 3;21:283. doi: 10.1186/s12859-020-03606-2

Table 2.

Predicting ASCVD risk with GRS (genetic risk score) and traditional risk factors

Model 1 Model 2
OR p-value CI OR p-value CI
GRS 2.354 <.001 (1.466, 3.779) 2.348 <.001 (1.460, 3.776)
age 1.155 <.001 (1.065, 1.254) 1.158 <.001 (1.067, 1.256)
sex (M vs F) 0.771 0.6954 (0.242, 2.459)
AUC 0.8428 vs 0.743 (Ref) 0.8441 vs 0.743 (Ref)

Ref represents reference ROC; model with no risk score