Table 3.
Groups | Taurocholic acid | Taurochenodeoxycholic acid | Chenodeoxycholic acid glycine conjugate | Glycocholic acid | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
VIP | Fold change | q-value | VIP | fold change | q-value | VIP | fold change | q-value | VIP | fold change | q-value | |
Pre vs. NC | 3.7255* | 121.63* | 0.0250* | 2.9581* | 33.078* | 0.0442* | 2.5999* | 6.2715* | 0.0106* | 2.9258* | 9.1140* | 0.0151* |
P1 vs. Pre | 0.1995 | 0.8706 | 0.58367 | 0.9535 | 0.6365 | 0.3168 | 1.4928 | 0.6484 | 0.1004 | 0.9049 | 1.1897 | 0.3272 |
P3 vs. P1 | 1.0553 | 2.1777 | 0.5727 | 0.3641 | 1.8009 | 0.7085 | 0.5288 | 1.1475 | 0.6667 | 1.7125 | 1.8460 | 0.3533 |
P7 vs. P3 | 0.6284 | 0.3481 | 0.9997 | 0.1090 | 0.32701 | 0.9997 | 0.7702 | 1.1803 | 0.9997 | 0.0039 | 1.3490 | 0.9999 |
P7 vs. NC | 3.7079* | 80.275* | 0.0243* | 1.9267 | 12.399 | 0.1930 | 1.2458 | 5.5076 | 0.2866 | 2.9072* | 27.001* | 0.0384* |
VIP from the OPLS-DA greater than 1.0, q-value <0.05 and fold change ≤0.8 or ≥1.2 indicates the difference between the 2 groups was significantly.