TABLE 3.

Prokaryote ASVs with highest functional coreness in the dataset of the co-culture experiment.

			Host state				BLAST top-hit
Module	ASV code	Functional coreness	Medium A	Medium B	Medium C	Taxon	Description	Cover	Identity	Accession
1	asv_0041	239.4	12.547	−6.274	−6.262	Bacteria	Mucilaginibacter oryzae	100%	98.42%	AB682426.1
	asv_0125	225.3	11.660	−5.835	−5.831	Bacteria	Mucilaginibacter herbaticus	100%	99.60%	NR_109510.1
	asv_0047	83.8	17.267	−8.640	−8.637	Bacteria	Terriglobus roseus	100%	100.00%	LT629690.1
	asv_0018	77.4	19.123	−10.071	−9.024	Bacteria	Paraburkholderia kirstenboschensis	100%	100.00%	MN204221.1
	asv_0058	67.2	17.950	−8.964	−8.953	Bacteria	Mucilaginibacter boryungensis	100%	99.21%	NR_108986.1
3	asv_0050	345.3	7.875	−3.949	−3.933	Bacteria	Mucilaginibacter puniceus	100%	99.21%	NR_152668.1
	asv_0153	100.0	5.708	−2.858	−2.850	Bacteria	Sphingomonas polyaromaticivorans	100%	99.21%	LN890119.1
	asv_0118	57.0	6.635	−3.339	−3.328	Bacteria	Bdellovibrio bacteriovorus	100%	96.84%	KX450994.1
	asv_0131	41.3	7.592	−3.804	−3.782	Bacteria	Clostridium pasteurianum	100%	100.00%	CP003261.1
	asv_0088	39.8	9.018	−3.634	−5.396	Bacteria	Pelosinus fermentans	100%	98.81%	CP010978.1

For the two network modules with the highest specificity values for Medium A [s_module(h,j); Figure 6], top-5 ASVs with highest functional coreness are shown. A functional coreness score, specificity for media [s(i,j)], and NCBI BLAST top-hit results are indicated for each ASV.