Table 1.
DiaGene and Hoorn DCS baseline cohort characteristics
| DiaGene (n=1815) |
Hoorn DCS (n=1518) |
|
| Male sex, n (%) | 977 (53.80) | 854 (56.26) |
| Age (year) | 65.21 (10.58) | 64.48 (10.63) |
| Age of onset of diabetes (year) | 54.94 (11.73) | 57.29 (11.03) |
| Duration of diabetes (year) | 10.04 (8.43) | 7.17 (5.81) |
| BMI (kg/m2) | 30.46 (5.45) | 30.39 (5.40) |
| HbA1c (mmol/mol) | 53.31 (11.58) | 50.63 (11.33) |
| HbA1c (%) | 7.03 (1.06) | 6.78 (1.04) |
| MAP (mm Hg) | 98.90 (10.82) | 98.82 (11.31) |
| Total cholesterol (mmol/L) | 4.29 (0.93) | 4.63 (1.65) |
| Triglycerides (mmol/L) | 1.70 (1.13) | 1.82 (1.05) |
| HDL-cholesterol (mmol/L) | 1.71 (0.32) | 1.18 (0.39) |
| Non-HDL-cholesterol (mmol/L) | 3.12 (0.90) | 3.46 (1.48) |
| LDL-cholesterol (mmol/L) | 2.45 (0.83) | 2.62 (0.89) |
| eGFR MDRD | 77.30 (22.47) | 84.30 (21.73) |
| Smoking, n (%) | ||
| Never | 25.9 | 60.5 |
| Former | 56.2 | 21.3 |
| Current | 17.9 | 17.3 |
| Cardiovascular disease (%) | 34.6 | 15.5 |
| Nephropathy (%) | 20.2 | 19 |
| Medication use (%) | ||
| Metformin | 51.1 | 68.3 |
| SU derivatives | 28.4 | 15.5 |
| Insulin | 29.6 | 25.1 |
| ACE inhibitors/ARB | 53.3 | 37.2 |
| Statins | 64.4 | 69.6 |
Unless stated otherwise, mean (±SD) are given.
ARB, angiotensin II receptor blocker; BMI, body mass index; DCS, Diabetes Care System; eGFR, estimated glomerular filtration rate; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MAP, mean arterial pressure; MDRD, Modification of Diet in Renal Disease; SU, sulfonylurea.