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Programmed cell death-ligand 1 (PD-L-1) pathway. (A) Upregulation of programmed cell death protein 1 (PD-1) pathway leads to increased inhibition of T cell/ immune response. (B) Inhibition of the PD-1 pathway via anti-PD-L1 leads to upregulation of immune response. MHC, major histocompatibility complex; TCR, T cell receptor.
