TABLE 2.
Sentinel genetic lesions of 25 BCR‐ABL1‐like ALL
Genetic lesions | No (%) |
---|---|
ABL‐class fusions | 3 (12) |
EBF1‐PDGFRB | 2 (8) |
RANBP2‐ABL1 | 1 (4) |
CRLF2 rearrangements | 2 (8) |
IGH‐CRLF2 | 2 (8) |
JAK‐STAT pathway mutations | 3 (12) |
IL7R mutation | 1 (4) |
FLT3 mutation | 2 (8) |
RAS pathway mutations | 17 (68) |
NRAS | 8 (32) |
KRAS | 3 (12) |
NRAS and KRAS | 1 (4) |
NRAS and NF1 | 1 (4) |
PTPN11 | 3 (12) |
NF1 | 1 (4) |