Table 3.
Multivariable analysis of factors associated with duration of abiraterone treatment
Factors | Hazard ratio (95%CI) | P value |
---|---|---|
ECOG status | ||
≤1 | 1.00 | |
>1 | 1.75 (0.96‐3.44) | .068 |
PSA at AA initiation (ng/mL) | ||
≤61 | 1.00 | |
>61 | 2.04 (1.10‐3.79) | .024 |
PSA response* | ||
No | 1.00 | |
Yes | 0.42 (0.22‐0.80) | .008 |
Chemotherapy status | ||
Chemo‐naïve | 1.00 | |
Post‐chemo | 1.91 (1.03‐3.54) | .040 |
Abbreviations: AA, abiraterone acetate; CI, confidence interval; ECOG, Eastern Cooperative Oncology Group.
≥50% PSA decline from baseline within 12 wks.
Colour shaded values indicates statistical significant P‐values.