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. 2020 Jun 17;10(6):200084. doi: 10.1098/rsob.200084

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© 2020 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 5. — The graphical representation of the effects of standard chow and antioxidant supplementation for three months on mean plaque numbers in the brains of 15-month-old female APP transgenic mice. Controls were APP transgenic mice fed Std Chow (n = 7), Mega E were APP transgenic mice fed Std Chow supplemented with a high dose of vitamin E acetate at 64.8 gm kg of feed (n = 6), Megacombo were APP transgenic mice fed a combination of antioxidants including vitamin E acetate at 28.8 gm kg⁻¹ of feed vitamin C palmitate at 28.8 gm kg⁻¹ of feed, Ginkgo biloba at 3.6 m kg⁻¹ of feed and grape seed extract (Pycnogenol) at 3.6 gm kg⁻¹ of feed (n = 6). Statistical analysis using a Kruskal–Wallis non-parametric ANOVA demonstrated a statistically significant difference between the control group and the megacombo group (p < 0.01).