Table 3. Comparison between patients with isolated chronic inducible urticaria and those with chronic inducible urticaria associated with chronic spontaneous urticaria.

Demographic characteristics	Chronic inducible urticaria (n=76)	Chronic inducible urticaria + chronic spontaneous urticaria (n=42)	p value
Female sex*	73.7	95.2	0.03
Current age, years†	41.3±13.5	41.0±12.5	NS
Age at onset, years†	36.9±14.7	35.6±14.6	NS
Time of disease, years†	4.5±5.2	5.7±7.2	NS
Response to treatment*
Response to AH1 at licensed dose	32.9	19.0	NS
Response to AH1 at a dose up to 4-fold higher than the licensed dose	30.3	42.9	NS
Refractory to AH1	36.8	38.1	NS
Time to response to treatment, months†	15.0	19.8	0.02

* Fisher’s test. ^† Mann-Whitney test.

Results expressed by % or mean±standard deviation.

AH1: antihistamine; NS: not significant.