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. 2020 Jun 29;13:6191–6202. doi: 10.2147/OTT.S253861

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© 2020 Chen et al.

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UBE2O expression is elevated in HNSCC samples. (A) UBE2O transcripts in HNSCC tissues and corresponding noncancerous adjacent tissues from the public TCGA dataset were analyzed. (B) Frequencies of UBE2O alterations, including amplification, mRNA upregulation, truncation and missense mutations, from the HNSCC TCGA database were analyzed. (C) Survival prognosis of patients with HNSCC based on UBE2O transcript level. (D) Representative images of UBE2O protein expression in HNSCC tissues and adjacent noncancerous epithelial tissues determined by immunohistochemistry. Original magnification: 200×. (E) Expression of UBE2O protein in HNSCC tissues and adjacent noncancerous epithelial tissues (***P < 0.001).